Parkinson’s Disease MCQs
Parkinson’s disease comes under the category of extrapyramidal disorders. Let’s go through the following MCQs and learn about Parkinson’s disease. You can refer a textbook while doing these questions. Click here to download textbooks for free
The case of tremor
- A 76 year old male presents to you with repetitive uncontrolled movements in the body. You examine the patient. Then you observe coarse tremors. What are the possible causes? (Select one or more)
- Senile tremor
- Intention tremor
- Parkinson’s disease
- Which of the following description of tremor will tally with Parkinsonian tremor?
- Tremor occurs with action. But disappears during resting.
- Tremor is there in both action and with resting.
- Resting tremor which disappears with action
- Fine generalized tremor
- Tremor with outstretched hands
Aetiology of Parkinson’s disease
- Which of the following factors are in favor of the diagnosis of Parkinson’s disease? (Select one or more)
- Age more than 75 years
- Male sex
- Urban living
- Use of pesticides
- Regarding PD, select all the true statements.
- It doesn’t have a genetic predisposition.
- Caused by loss of dopaminergic neurons in substantia nigra
- The extent of dopaminergic cell loss doesn’t correlate with the degree of akinesia
- At presentation usually about 70% of the dopaminergic neurons are lost.
- Pathological process starts many years before the onset of symptoms
Answers for MCQs on Parkinson’s disease
- (T,T,T,F,F) These are the courses for coarse tremors. Parkinsonism, intention tremor, flapping tremor (in hepatic pre-coma), sometimes in senile tremor and Wilson’s disease. However, anxiety and thyrotoxicosis cause fine tremors. Watch this video to have some idea about Parkinsonian tremor
- Parkinsonian tremor is a resting tremor which disappears with resting. Also, it is a coarse tremor.
- (T, T, F, T, T) Increasing age more than 70 is a risk factor. Also, prevalence is higher in males and in smokers. The incidence is higher in rural living people. MPTP which is a mitochondrial toxin present in pesticides are thought to be associated with the pathogenesis of PD.
- (F, T, F, T, T) PD is caused by loss of dopaminergic neurons in substantia nigra. This process starts long time before the onset of symptoms. Therefore, at presentation there is about 70% of neuronal loss. The degree of akinesia correlates with the extent of neuronal loss. Also, twin studies show a strong component of genetic predisposition specially in those who are having early onset (<40) PD.