- In hepatitis B infection:
- The presence of delta agent is indicative of chronic infection
- Minimal change glomerulonephritis is a recognized complication
- Anicteric neonatal infection often results in persistent infection
- 10% of patients have splenomegaly
- Anti-HBs antibody implies past infection with hepatitis B
- (F, F, T, T, F) Hepatitis B is a DNA virus transmitted parenterally. HBsAg is seen in the serum 1-5 months after exposure (presence after 6 months implies carrier state and is seen in 5-10%). HBeAg is seen 6-12 weeks after exposure and implies high infectivity (persistence >12 weeks implies chronic infection). Anti-HBc implies previous exposure; anti-HBs alone is seen with vaccination. The glomerulonephritis associated with hepatitis B infection is membranous rather than minimal change.